Welcome to the Gerarduzzi Lab
About our lab
Studying the Interface between Extracellular and Intracellular Signalling
Our lab is interested in studying novel proteins and their mechanisms in kidney repair after injury and their implications in renal fibrosis during early adaptive repair and into late stage disease.
The extracellular matrix is a dynamic and flexible structure that plays a crucial role in maintaining cellular homeostasis by mediating outside external signals to the surrounding cells. Understanding the cross-talk between cell-ECM interactions is key to studying a variety of pathologies which stem a dysregulated cell matrix.
Both acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are known to have a blockage in p53 function, which hinders conventional therapies like chemo- and radio-therapy. Our lab is interested in studying p53 regulation in leukemia with the goal of developing new strategies to restore p53 function necessary for cancer treatments.
Thanks for your interest in our research. Get in touch with us for any questions or comments regarding our work and publications. We’d love to hear from you.
5415 Assumption Blvd, Montreal, QC H1T 2M4
514-252-3400 x3352 (Lab Phone)